"He’s quite the marvel, a very fine actor. He’s a lovely guy, very disciplined, very focused.
"He called me up and said, ‘This is Andrew Garfield’ and I said, ‘Who?’ and he said, ‘Uh, we’re in the movie together…’ and I said, ‘Yeah, what part do you play?’ and he said, ‘Uh, I play your nephew!’ I liked him instantly.
"We had a wonderful lunch and laughed and joked and he said, "Just feel free to bring whatever you like" and I said, "absolutely." The guy who’s directing takes a beating because his last name is Webb! But he’s lovely."
Questioned about how Garfield was handling the physical side of the role, Sheen said: "He’s very athletic, he’s in great shape. He plays basketball and he works out every day. He’s fit. Very wiry, thin, tall, very physically focused.
"He works in a very organic way – he loves accidents, when something happens in a scene that causes him to do something else. I went through a couple of very emotional scenes and he was right there, focused.
"And he was the same off camera. He didn’t slack off. No, sir! He was equally emotional off camera. Very impressive. He’s going to be a huge star."
The Amazing Spider-Man opens in theaters on July 3, 2012.